Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats

Table 1 Effects of alcohol intake alone and following administration of either NS or TQ on the contents of MDA and GSH and activities of SOD, GSH and CAT in rat gastric tissue (means ± SD)

Parameters	Control	Ethanol	Eth + NS	Eth + TQ
MDA (nmol/g proteine)	136.33 ± 11.42	329.43 ± 19.80a	112 ± 17.16c	201.15 ± 29.11c
GSH (μmol/g proteine)	0.84 ± 0.04	0.44 ± 0.03a	0.54 ± 0.05c	0.42 ± 0.02
SOD (U/g proteine)	47.39 ± 5.74	17.75 ± 3.02a	56.88 ± 4.09c	51.08 ± 3.17c
GST (nmol/min/g proteine)	4.39 ± 0.29	1.81 ± 0.32a	4.02 ± 0.31c	4.07 ± 0.28c
CAT (U/g proteine)	56.45 ± 3.30	59.5 ± 7.99	55.63 ± 6.52	54.18 ± 10.19

^aP<0.05 vs control group.

^cP<0.05 vs alcohol group.