Antitumor and synergistic effect of Chinese medicine “Bushen huayu jiedu recipe” and chemotherapy on transplanted animal hepatocarcinoma

Table 1 Inhibition of BSHYJDR on hepatocarcinoma H₂₂

Group	Dose (mg/kg)	Mice (n) (before/after)	Tumor weight (g) (mean±SD)	RR (%)
Model	–	10/10	1.30±0.73	–
DDP	1×4	10/10	0.41±0.09b	68.46
BSHYJDR	26 600×10	10/10	0.69±0.29ad	46.92
BSHYJDR	13 300×10	10/10	0.85±0.34d	34.62

^aP<0.05,

^bP<0.01 vs control group,

^dP<0.01 vs DDP group.

Table 2 Synergistic effect of BSHYJDR and DDP on hepatocarcinoma H₂₂

Group	Doses (mg/kg)	Mice (n) (before/after)	Tumor weight (g) (mean±SD)	RR (%)
Model	–	10/10	1.30±0.73	–
DDP	1×4	10/10	0.41±0.09b	68.46
DDP+BSHYJDR	1×4+26 600×10	10/10	0.29±0.17d	77.69
DDP+BSHYJDR	1×4+13 300×10	10/10	0.38±0.21b	70.77

^bP<0.01,

^dP<0.001 vs control group.