Prevalence of porcine endogenous retrovirus in Chinese pig breeds and in patients treated with a porcine liver cell-based bioreactor

Table 1 PERV-RT activities of patient’s sera and Chinese experimental mini-pig tissues (U/mL)

	Pre-treatment	0 d after treatment	14 d after treatment	30 d after treatment
Patient 1	1.366	1.54	1.5	1.612
Patient 2	1.612	1.44	1.44	1.612
Patient 3	1.654	1.523	1.443	1.578
Mean±SD	1.544 ± 0.1555761	1.501 ± 0.0535071	1.461 ± 0.0338081	1.6006667 ± 0.019631
Normal control (Mean±SD)	1.441 ± 0.102	1.451667 ± 0.1198012	1.525667 ± 0.0850312	1.468333 ± 0.0850312

¹PERVs-RT activities before treatment were not significantly different when compared with post-treatment;

²normal control groups (P > 0.05).

Table 2 PERV-RT activities of pig tissues of Chinese experimental mini-pig and domestic pig breeds (U/mL)

	Musclesupernatants	Liversupernatants	Serum
Chinese experimental	2.34	2.04	2.49
mini-pig1
Chinese experimental	2.53	2.35	2.48
mini-pig2
Chinese experimental	2.46	2.38	2.54
mini-pig3
mean±SD	2.443333 ± 0.09609a	2.256667 ± 0.188237a	2.503333 ± 0.032146a
Taihu pig	4	3.4	3.44
Wuzhishan pig	3.7	4.3	2.56
Dabai pig	3.49	3.08	2.95
Dahei pig	3.39	3.77	3.22
mean±SD	3.4950 ± 1.43875	3.6375 ± 0.523983	3.0425 ± 0.378979
Human normal control	-	-	1.440 ± 1.0641

^aP<0.05 vs normal human control group.