Copyright
©The Author(s) 2005.
World J Gastroenterol. Aug 14, 2005; 11(30): 4618-4622
Published online Aug 14, 2005. doi: 10.3748/wjg.v11.i30.4618
Published online Aug 14, 2005. doi: 10.3748/wjg.v11.i30.4618
Specimen | Gene mutation | |
Carcinoma | Corresponding adjacent normal tissue | |
H1 | - | - |
H2 | - | - |
H3 | - | - |
H4 | 660 nt A→G | - |
H5 | 462 nt G→T, | - |
177-234 nt deletion | ||
H6 | - | - |
H7 | 64 nt G→C, 665 nt T→C | - |
H8 | 462 nt G→T, 660 nt A→G, | 660 nt A→G |
177-234 nt deletion | ||
H9 | - | - |
H10 | 177-234 nt deletion, | - |
454 nt T→C 466 nt G→A | ||
H11 | - | - |
H12 | 375 nt A→G | - |
177-234 nt deletion | ||
H13 | - | - |
H14 | - | |
H15 | 454 nt T→C, 466 nt G→A | - |
H16 | 177-234 nt deletion | - |
H17 | 737 nt A→T, 740 nt A→G | - |
H18 | - | - |
H19 | - | - |
H20 | - | - |
H21 | 462 nt G→T | - |
H22 | - | - |
H23 | - | - |
H24 | - | - |
H25 | 177-234 nt deletion, | - |
660 nt A→G | ||
H26 | 177-234 nt deletion | - |
H27 | - | - |
H28 | 613 nt A→T | - |
H29 | - | - |
H30 | - | - |
Specimen | Gene mutation | |
Carcinoma | Corresponding adjacent normal tissue | |
N1 | 670 nt A→G | – |
N2 | 660 nt A→G | – |
N8 | 660 nt A→G | – |
N16 | 613 nt A→T | – |
N22 | 670 nt A→G | – |
Mutation code | Gene variation | Amino acid variation | Mutation |
1 | 375 nt A→G | 88 nt Ile→Val | |
2 | 454 nt T→C | 114 nt Phe→Ser | |
3 | 462 nt G→T | 117 nt Glu→termination | Termination |
codon | mutation | ||
4 | 466 nt G→A | 118 nt Gly→Glu | |
5 | 613 nt A→T | 167 nt Lys→Ile | |
6 | 648 nt G→C | 179 nt Gly→Arg | |
7 | 660 nt A→G | 183 nt Arg→Gly | |
8 | 665 nt T→C | 184 nt Gly→Gly | Synonymous |
mutation | |||
9 | 670 nt A→G | 186 nt Glu→Gly | |
10 | 737 nt A→T | 208 nt Pro→Pro | Synonymous |
mutation | |||
11 | 740 nt A→G | 209 nt Lys→Lys | Synonymous |
mutation | |||
12 | 177–234 nt deletion | Frameshift | |
mutation | |||
Termination | |||
mutation |
- Citation: Zhao GQ, Wang T, Zhao Q, Yang HY, Tan XH, Dong ZM. Mutation of DNA polymerase β in esophageal carcinoma of different regions. World J Gastroenterol 2005; 11(30): 4618-4622
- URL: https://www.wjgnet.com/1007-9327/full/v11/i30/4618.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i30.4618