Clinical evaluation of serum concentrations of intercellular adhesion molecule-1 in patients with colorectal cancer

Table 1 Colorectal cancer patients and disease characteristics

Stage	n	%
Dukes A1	3	5.36
Dukes A2,3	6	10.71
Dukes B	21	37.50
Dukes C and D	26	46.43
Histologic differentiation
Highly	22	39.29
Moderate	24	42.86
Poorly	10	17.85
Localization
Right colon	17	30.36
Left colon	21	37.5
Rectum	18	32.14

Table 2 Correlation between soluble ICAM-1 concentrations and clinicopathologic factors in colorectal cancer

Factors	n	ICAM-1 (mean±SD, μg/L)	χ2	P
Clinical staging
Dukes A1	3	352.63 ± 61.82a
Dukes A2,3	6	491.17 ± 86.36	2.88 < 0.05
Dukes B	21	496.82 ± 93.04d	0.18 > 0.05
Dukes C and D	26	743.68 ± 113.74	12.38 < 0.001
Grade of differentiation
Highly differentiated	22	410.23 ± 67.47b
Differentiated	24	486.53 ± 103.64d	4.08 < 0.01
Poorly differentiated	10	736.49 ± 121.967	10.48 < 0.001
Metastasis
Liver	3	769.19 ± 127.32
Lymph node positive	23	756.25 ± 125.57d	0.32 > 0.05
Lymph node negative	30	445.62 ± 69.18	16.98 < 0.001

^aP < 0.05, Dukes A₁vs Dukes A_2,3;

^bP < 0.01, highly differentiated vs differentiated;

^dP < 0.001, Dukes B vs Dukes C and D; Differentiated vs poorly differentiated; lymph node positive vs lymph node negative.