5-Fluorouracil concentration in blood, liver and tumor tissues and apoptosis of tumor cells after preoperative oral 5’-deoxy-5-fluorouridine in patients with hepatocellular carcinoma

Table 1 5-FU concentrations in blood, liver and tumor after oral 5’-DFUR

Tissue	Level of 5-FU
Plasma (µg/mL)	1.1 ± 0.3a
Liver tissue (µg/g)	5.6 ± 0.8
Central tissue of tumor (µg/g)	5.9 ± 0.9
Periphery tissue of tumor (µg/g)	10.5 ± 1.6a

^aP < 0.05 vs 5-FU concentration in liver tissue.