Expression and significance of tumor-related genes in HCC

Table 1 Expression of DEK, cyclin D1, IGF-II, GPC3, rpP0 mRNAs in HCC and adjacent noncancerous liver tissues

	Cyclin D1a		GPC3c		DEKe		IGFg		rpP0i
	T	N	T	N	T	N	T	N	T	N
Positive	28	13	24	7	25	5	28	12	26	10
Negative	4	19	8	25	7	27	4	20	6	22

T, HCC tumor tissue; N, adjacent nontumorous tissue. χ²-test:

^aP < 0.05,

^cP < 0.05,

^eP < 0.05,

^gP < 0.05,

ⁱP < 0.05 vs others.

Table 2 Expression of DEK, cyclin D1, IGF-II, GPC3, rpP0 mRNAs in well- and poorly-differentiated HCC

	Cyclin D1		GPC3		DEK		IGF-II		rpP0
	+	-	+	-	+	-	+	-	+	-
Well-differentiated HCC	6	3	6	3	8	1	6	3	7	2
Poor-differentiated HCC	22	1	18	5	17	6	22	1	19	4
Total	28	4	24	8	25	7	28	4	26	6

Table 3 Expression of DEK, cyclin D1, IGF-II, GPC3, rpP0 mRNAs in HCC with AFP negative and positive HCC tissue

	n	Cyclin D1+	GPC3+	DEK+	IGF-II+	rpP0+
AFP(-)	10	8	9	9	9	9
AFP(+)	22	20	15	16	19	17
Total	32	28	24	25	28	26

χ² test, P > 0.05, the group of APF(+) vs the group of AFP(-).

Table 4 Expression of DEK, cyclin D1, IGF-II, GPC3, rpP0 mRNAs in HCC and adjacent noncancerous liver tissues by multiplex RT-PCR Groups

	n	Positive reaction		Negative reaction
		Anyone of the five mRNAs (%)	All of the five mRNAs (%)	Anyone of the five mRNAs (%)	All of the five mRNAs (%)
T	32	32 (100)	22 (68.8)	10 (31.3)	0 (0)
N	32	24 (75.0)	3 (9.4)	29 (90.6)	8 (25.0)
		P > 0.05	P > 0.05	P > 0.05	P > 0.05