Clinical significance of expression of apoptotic signal proteins in gastric carcinoma tissue

Table 1 Expressions of FADD, TRADD, FasL, Fas and NFκB proteins in gastric carcinoma tissue specimens, n (%)

Sex	n	FADD	TRADD	FasL	Fas	NFκB
Male	35	12 (34.3)	26 (74.3)	25 (71.4)	21 (60.0)	28 (80.0)
Female	20	8 (40.0)	12 (60.0)	13 (65.0)	12 (60.0)	15 (75.0)
	55	20 (36.4)	38 (69.1)	38 (69.1)	33 (60.0)	43 (78.2)

Table 2 Relationship between expressions of the FADD, TRADD, FasL, Fas, NFκB proteins and clinical characteristics, n (%)

Clinical characteristics	n	FADD	TRADD	FasL	Fas	NFκB
Male	35	12 (34.3)	26 (74.3)	25 (71.4)	21 (60.0)	28 (80.0)
Female	20	8 (40.0)	12 (60.0)	13 (65.0)	12 (60.0)	15 (75.0)
Age/yr ≤ 45	22	8 (36.4)	14 (63.6)	16 (72.7)	13 (59.1)	16 (72.7)
> 45	33	13 (39.4)	24 (72.7)	22 (66.7)	20 (60.6)	27 (81.8)
Tumor
Size ≤ 5 cm	17	8 (47.1)	11 (64.7)	14 (82.4)	15 (88.2)a	14 (82.4)
> 5 cm	38	13 (34.2)	27 (71.1)	24 (63.2)	17 (44.7)	29 (76.3)
Grading I–II	14	11 (78.6)b	6 (42.9)	11 (78.6)	14 (100.0)c	11 (78.6)
III–IV	41	9 (22.0)	32 (78.1)	27 (65.9)	19 (46.3)	32 (78.1)
CEA ≤ 30 (µg/L)	8	5 (62.5)	0 (0.0)	5 (62.5)	0 (0.0)	5 (62.5)
> 30 (µg/L)	47	16 (34.0)	38 (80.9)d	33 (70.2)	33 (70.2)d	38 (80.9)
Tumor
transformation Yes	6	3 (50.0)	3 (50.0)	5 (83.3)	3 (50.0)	3 (50.0)
No	49	17 (34.2)	35 (71.4)	33 (67.4)	30 (61.2)	39 (79.6)

^aP < 0.05 vs size >5 cm;

^bP < 0.01,

^cP < 0.05 vs grading III–IV;

^dP < 0.01 vs CEA ≤ 30 (μg/L).