Gender differences in hepatic ischemic reperfusion injury in rats are associated with endothelial cell nitric oxide synthase-derived nitric oxide

Table 1 Degree of hepatocyte injury (determined by a point-counting method with an ordinal scale) (n = 4, mean±SD).

	Grade 0 (%)	Grade 1 (%)	Grade 2 (%)	Grade 3 (%)
MS	99.4±0.1	0.6±0.1	0	0
FS	99.4±0.2	0.6±0.2	0	0
M	0.2±0.1b	8.6±1.7b	76.9±2.4b	14.4±7.2b
F	2.7±1.0df	37.2±3.7df	52.2±3.2df	7.9±1.4da
F+L-NAME	1.0±0.3c	16.0±4.6h	75.1±4.1h	8.0±1.0
M+E2	4.0±1.2f	57.7±3.9f	32.9±5.3f	5.5±0.5f
M+E2+L-NAME	1.6±0.6e	28.5±1.9j	62.3±3.1j	7.6±1.3e

There were no significant differences between MS and FS groups with respect to degree of hepatocyte injury.

^bP<0.01 vs MS group.

^dP<0.01 vs FS group.

^aP<0.05 vs M group,

^fP<0.01 vs M group.

^cP<0.05 vs F group,

^hP<0.01 vs F group.

^eP<0.05 vs M+E₂ group,

^jP<0.01 vs M+E₂ group.