Effects of long-term ethanol consumption on jejunal lipase and disaccharidase activities in male and female rats

Table 1 Initial body weight, final body weight, liver weight, and relative liver weight in each group^1-4.

Groups	MC	ME	FC	FE	ANOVA
					Gender	Ethanol	Gender×ethanol
Body weight(g)
Initial	205±7	201±9	190±1	184±3	0.0113	NS	NS
Final	282±6	260±12	223±6	206±4	0.0001	0.0184	NS
Liver weight (g)
Relative liver	9.26±0.53	9.81±0.77	6.12±0.27	7.05±0.30	0.0001	NS	NS
weight (%)5	3.34±0.15	3.73±0.17	2.88±0.09	3.33±0.10	0.0072	0.0024	NS

¹Four groups were designed as follows: male control group (MC), male ethanol group (ME), female control group (FC), and female ethanol group (FE). ²Data are mean±SE (n = 10). ³Values in the same row with different superscripts are significantly different (P<0.05). ⁴Analyzed by two-way ANOVA; NS, no significant difference.

⁵Relative liver weight = liver weight/body weight×100%.

Table 2 Plasma AST and ALT activities in each group^1-4.

Groups	MC	ME	FC	FE	ANOVA
					Gender	Ethanol	Gender×ethanol
At the beginning of experiment
AST (U/L)	86±3	87±2	81±2	82±2	0.0286	NS	NS
ALT (U/L)	28±1	28±1	24±1	24±1	0.0003	NS	NS
At the termination of experiment
AST (U/L)	95±10	150±12	126±8	203±16	0.0010	0.0001	NS
ALT (U/L)	38±03	073±05	033±1	095±13	NS	0.0001	NS

^1-4Details as same as in Table 1.

Table 3 Jejunal lipase and disaccharidase activities in each group^1-4.

Groups	MC	ME	FC	FE	ANOVA
					Gender	Ethanol	Gender×ethanol
Specific activities (U/g protein)
Lipase	485±175	1093±264	458±123	891±137	NS	0.0074	NS
Sucrase	260±37	95±16	225±37	129±15	NS	0.0001	NS
Maltase	781±108	295±49	671±111	363±30	NS	0.0001	NS
Lactase	132±20	43±6	106±17	51±4	NS	0.0001	NS

^1-4Details as same as in Table 1.