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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Apr 14, 2005; 11(14): 2117-2123
Published online Apr 14, 2005. doi: 10.3748/wjg.v11.i14.2117
Published online Apr 14, 2005. doi: 10.3748/wjg.v11.i14.2117
Parameter | n | β-catenin | c-myc | cyclinD1 | MMP-7 | ||||
Normal | Abnormal | + | - | + | - | + | - | ||
Mass size (cm) | |||||||||
<3 | 9 | 3 | 6 | 6 | 3 | 6 | 3 | 6 | 3 |
3-5 | 15 | 4 | 11 | 11 | 4 | 10 | 5 | 10 | 5 |
>5 | 23 | 8 | 15 | 16 | 7 | 19 | 4 | 14 | 9 |
Histological grade | |||||||||
I | 10 | 4 | 6 | 5 | 5 | 4 | 6 | 7 | 3 |
II | 16 | 6 | 10 | 11 | 5 | 12 | 4 | 11 | 5 |
III | 21 | 5 | 16 | 17 | 4 | 19a | 2 | 12 | 9 |
Proliferation degree | |||||||||
High | 28 | 6 | 22 | 23 | 5 | 25 | 3 | 16 | 12 |
Low | 19 | 9 | 10 | 10c | 9 | 10c | 9 | 14 | 5 |
Metastasis | |||||||||
Positive | 25 | 4 | 21 | 19 | 6 | 20 | 5 | 20 | 5 |
Negative | 22 | 11e | 11 | 14 | 8 | 15 | 7 | 10e | 12 |
Survival time (yr) | |||||||||
>1 | 13 | 8 | 5 | 8 | 5 | 9 | 4 | 4 | 9 |
≤1 | 34 | 7g | 27 | 25 | 9 | 26 | 8 | 26g | 8 |
β-catenin | n | cyclinD1 | c-myc | MMP-7 | |||
+ | - | + | - | + | - | ||
Normal | 6 | 0 | 6 | 0 | 6 | 1 | 5 |
Abnormal | 6 | 6 | 0 | 5 | 1 | 6 | 0 |
β-catenin | n | CyclinD1 (%) | c-myc (%) | MMP-7 (%) | |||
+ | - | + | - | + | - | ||
Normal | 15 | 7 | 8 | 6 | 9 | 5 | 10 |
Abnormal | 32 | 28 (87.5) | 4 | 27 (84.5) | 5 | 25 (78.1) | 7 |
- Citation: Li YJ, Wei ZM, Meng YX, Ji XR. β-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: Relationships with carcinogenesis and metastasis. World J Gastroenterol 2005; 11(14): 2117-2123
- URL: https://www.wjgnet.com/1007-9327/full/v11/i14/2117.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i14.2117