Significance of glucocorticoid receptor expression in colonic mucosal cells of patients with ulcerative colitis

Table 1 Details of primary polyclonal antibodies used against GRα and GRβ.

Antibody	Antibodies against	Source	Clone	Dilution	Positive control
P-20	GRa	Santa Cruz	sc-1002	0.1111111	PBMC
Ab-1	GRb	Oncogene	pc171	0.3194444	PBMC

Table 2 GRα and GRβ expression in ulcerative colitis with different response.

	Expression of GRαa					Expression of GRβa
	-	+	++	+++	Total (n)	-	+	++	+++	Total (n)
Resistant	0	3	5	1	9	0	0	1	8	9
	0	0	7	9	16	0	4	5	7	16

There is a significant association between GRα/GRβ expression and the response of ulcerative colitis to GCs (^aP<0.05).

Table 3 GRα and GRβ expression in ulcerative colitis with different severity.

	Expression level of GRαa					Expression level of GRβa
	-	+	++	+++	Total (n)	-	+	++	+++	Total (n)
Mild	0	1	2	5	8	0	1	3	4	8
Moderate	0	1	7	3	11	0	2	2	7	11
Severe	0	1	3	2	6	0	1	1	4	6

There is a significant association between GRα/GRβ expression and the degree of inflammation of ulcerative colitis (^aP<0.05).