Expression of hypoxia-inducible factor 1α and vascular endothelial growth factor in hepatocellular carcinoma: Impact on neovascularization and survival

Table 1 Association between expression of HIF-1α and VEGF with clinicopathological data in HCC.

	n	HIF-1a		VEGF		P
		-	+	-	+
AFP concentration (ng/mL)
≤50	14	2	12	2	12
>50	22	10	12	2	20	>0.05
Cirrhosis
With	25	10	15	4	21
Without	11	2	9	0	11	>0.05
Edmondson grading
I-II	12	2	10	1	11
III-IV	24	10	14	3	21	>0.05
Tumor size (mm)
≤50	9	3	6	1	8
>50	27	9	18	3	24	>0.05
Microscopic venous invasion
With	24	3	21	1	23
Without	12	9	3	3	9	<0.05