Copyright
©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Jan 7, 2005; 11(1): 22-26
Published online Jan 7, 2005. doi: 10.3748/wjg.v11.i1.22
Published online Jan 7, 2005. doi: 10.3748/wjg.v11.i1.22
Table 1 Clinicopathologic features of gastric carcinoma in the elderly and young patients.
Variables | Age > 70 yr (n = 194) (%) | Age < 36 yr(n = 137) (%) | P value |
Age (yr) | 73.3±3.1 | 30.6±5.1 | <0.001 |
Gender | <0.001 | ||
Male | 131 (67.5) | 63 (46.0) | |
Female | 63 (32.5) | 74 (54.0) | |
Tumor size (cm) | 5.16±3.45 | 5.07±3.23 | NS |
Number of lesions | |||
Multiple | 14 (7.2) | 4 (2.9) | <0.05 |
Single | 180 (92.8) | 133 (97.1) | |
Borrmann type | |||
I | 10 (5.2) | 5 (3.6) | |
II | 43 (22.2) | 13 (9.5) | |
III | 128 (66.0) | 93 (67.9) | |
IV | 13 (6.6) | 26 (19.0) | 0.011 |
Location | |||
Upper | 16 (8.3) | 23 (16.8) | |
Middle | 41 (21.1) | 50 (36.5) | |
Lower | 130 (67.0) | 56 (40.9) | <0.05 |
Whole | 7 (3.6) | 8 (5.8) | |
Depth of invasion NS | |||
T1 | 37 (19.1) | 27 (19.7) | |
T2 | 39 (20.1) | 21 (15.3) | |
T3 | 96 (49.5) | 73 (53.3) | |
T4 | 22 (11.3) | 16 (11.7) | |
Histologic type | |||
Well-differentiated | 38 (19.5) | 4 (2.9) | |
Moderately differentiated | 62 (32.0) | 15 (10.9) | |
Poorly differentiated | 74 (38.1) | 84 (61.3) | <0.001 |
Mucinous | 10 (5.2) | 4 (2.9) | |
Signet ring cell | 6 (3.1) | 25 (18.3) | |
Others | 4 (2.1) | 5 (3.7) | |
Nodal involvement | NS | ||
N (-) | 88 (45.4) | 67 (48.9) | |
N (+) | 106 (54.6) | 70 (51.1) | |
Hepatic metastasis | NS | ||
N (-) | 188 (96.9) | 132 (96.4) | |
N (+) | 6 (3.1) | 5 (3.6) | |
Peritoneal dissemination | NS | ||
P (-) | 176 (90.7) | 116 (84.7) | |
P (+) | 18 (9.3) | 21 (15.3) | |
Stage | NS | ||
1 | 60 (30.9) | 41 (29.9) | |
2 | 41 (21.1) | 21 (15.3) | |
3 | 55 (28.4) | 36 (26.3) | |
4 | 38 (19.6) | 39 (28.5) | |
Operative type | |||
Total gastrectomy | 52 (26.8) | 47 (34.4) | 0.004 |
Subtotal gastrectomy | 122 (62.9) | 78 (56.9) | |
Others | 20 (8.6) | 12 (8.7) | |
Resectability | NS | ||
Curative | 157 (80.9) | 101 (73.7) |
Table 2 Correlation between prognostic factors and survival rates of elderly patients with gastric carcinoma.
Variables | No. of patients (n = 194) | 5-yr survival rate (%) | P value |
Gender | 0.3147 | ||
Male | 131 | 43.3 | |
Female | 63 | 52.8 | |
Tumor size (cm) | |||
<5 | 102 | 66.8 | |
>5 | 92 | 26 | |
Depth of invasion | <0.001 | ||
T1 and 2 | 76 | 84.9 | |
T3 and 4 | 118 | 20.6 | |
Histologic type | 0.0097 | ||
Differentiated | 100 | 55.1 | |
Undifferentiated | 94 | 39.8 | |
Tumor location | 0.1969 | ||
Upper third | 16 | 31.6 | |
Middle/distal third | 178 | 50.8 | |
Operative type | <0.001 | ||
Total | 52 | 27.9 | |
Subtotal | 142 | 55.5 | |
LN invasion | <0.001 | ||
N0 | 88 | 77.9 | |
N1 | 48 | 36.6 | |
>N2 | 58 | 12.9 |
Table 3 Multivariate analysis of factors associated with elderly patients with gastric carcinoma.
Variables | Odds ratio | 95% CI | P value |
Gender (male vs female) | 0.768 | 0.434-1.360 | NS |
Tumor location (upper vs distal) | 0.467 | 0.231-0.944 | NS |
Tumor size (cm) (<5 vs >5) | 1.618 | 0.942-2.778 | NS |
Depth of invasion (mucosa vs submucosa) | 1.061 | 0.924-1.217 | NS |
Histologic type (differentiated vs undifferentiated) | 2.041 | 1.244-3.350 | 0.005 |
Resectability (curative vs non-curative) | 3.077 | 1.681-5.635 | <0.001 |
Lymph node metastasis (negative vs positive) | 3.626 | 1.985-6.622 | <0.001 |
Age (yr) (>70 vs <70) | 1.308 | 0.845-1.107 | NS |
- Citation: Kim DY, Joo JK, Ryu SY, Park YK, Kim YJ, Kim SK. Clinicopathologic characteristics of gastric carcinoma in elderly patients: A comparison with young patients. World J Gastroenterol 2005; 11(1): 22-26
- URL: https://www.wjgnet.com/1007-9327/full/v11/i1/22.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i1.22