Expression and significance of angiopoietin-2 in gastric cancer

Table 1 Expression of Ang-2 in primary gastric cancers and adjacent normal tissues detected by semi-quantitative RT-PCR

	Cases	Ang-2 (mean ± SD)
Primary gastric cancers	72	0.497 ± 0.393a
Adjacent normal tissues	72	0.088 ± 0.224

^aP = 0.003 vs adjacent normal tissues.

Table 2 Correlation between expression of Ang-2 and VEGF in 72 primary gastric cancer detected by semi-quantitative RT-PCR

Ang-2 expression (Cases)	VEGF expression (Cases)		P value
	Positive	Negative
Positive	36	10	0.0055
Negative	12	14

Table 3 Correlation between pathological factors and Ang-2 expression in 72 primary gastric cancer

Pathological factors	No. of cases	Ang-2 mRNA (mean ± SD)	P value
Tumor stage
Early stage	26	0.222 ± 0.310
Advanced stage	46	0.593 ± 0.318	0.017
Histological type
Moderate-Poor differential type	45	0.425 ± 0.350	0.908
High differential type	27	0.203 ± 0.290
Lymph node metastasis
Positive	48	0.413 ± 0.346	0.752
Negative	24	0.490 ± 0.450
Serosal invasion
Positive	43	0.404 ± 0.327	0.764
Negative	29	0.334 ± 0.459
Vascular involvement
Positive	46	0.640 ± 0.335	0.032
Negative	26	0.272 ± 0.298