Effects of hemoperfusion adsorption and/or plasma exchange in treatment of severe viral hepatitis: A comparative study

Table 1 Comparison of liver function between pre- and post-therapy of hemoperfusion adsorption

	Pre-therapy	Post-therapy	t	P
ALT (IU/L)	80.3 ± 52.9	40.4 ± 15.2	2.628	< 0.01
AST (IU/L)	123.6 ± 57.8	79.9 ± 42.6	2.249	< 0.05
TB (μmol/L)	619.0 ± 193.9	403.3 ± 132.7	3.376	< 0.01
DB (μmol/L)	345.1 ± 125.4	233.6 ± 94.9	2.622	< 0.01
TSP (g/L)	63.9 ± 8.8	57.9 ± 8.7	1.359	> 0.05

ALT: alanine aminotransferase, AST: aspartate aminotransferase, TB: total bilirubin, DB: direct bilirubin, TSP: total serum proteins.

Table 2 Comparison of liver function pre- and post-therapy of plasma exchange

	Pre-therapy	Post-therapy	t	P
ALT (IU/L)	122.8 ± 115.5	70.8 ± 86.8	2.040	< 0.05
AST (IU/L)	147.7 ± 106.6	95.3 ± 81.6	2.214	< 0.05
TB (μmol/L)	488.3 ± 189.9	300.6 ± 135.9	4.596	< 0.01
DB (μmol/L)	244.4 ± 100.0	153.7 ± 73.6	4.152	< 0.01
TSP (g/L)	65.1 ± 9.2	57.7 ± 9.8	3.168	< 0.01

Table 3 Comparison of liver function pre- and post-therapy of plasma exchange plus hemoperfusion adsorption

	Pre-therapy	Post-therapy	t	P
ALT (IU/L)	109.45 ± 102.06	61.52 ± 74.19	2.594	< 0.02
AST (IU/L)	140.16 ± 94.71	90.59 ± 72.32	2.844	< 0.01
TB (mmol/L)	528.75 ± 200.57	332.16 ± 142.91	5.459	< 0.01
DB (mmol/L)	275.37 ± 118.01	178.00 ± 88.68	4.523	< 0.01
TSP (g/L)	64.70 ± 9.0	57.70 ± 9.5	3.312	< 0.01