Lakatos L, Mester G, Erdelyi Z, Balogh M, Szipocs I, Kamaras G, Lakatos PL. Striking elevation in incidence and prevalence of inflammatory bowel disease in a province of western Hungary between 1977-2001. World J Gastroenterol 2004; 10(3): 404-409 [PMID: 14760767 DOI: 10.3748/wjg.v10.i3.404]
Corresponding Author of This Article
Laszlo Lakatos, MD, 1st Department of Medicine, Csolnoky F. Province Hospital, Korhaz u.1, Veszprem, H-8200 Hungary. laklaci@hotmail.com
Article-Type of This Article
Clinical Research
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World J Gastroenterol. Feb 1, 2004; 10(3): 404-409 Published online Feb 1, 2004. doi: 10.3748/wjg.v10.i3.404
Table 1 Population of Veszprem Province between 1980-1998
Years
Total
Women
Men
1980
386.462
194.855
191.607
1990
379.246
192.867
186.462
1998
376.211
192.296
183.915
Table 2 Proportion of patients according to places of residence (in 1991) (OR: Odds ratio)
Urban (n)
Rural (n)
Total (n)
Veszprem Province
208.284
173.089
381.373
Ulcerative colitis
339
221
560
OR: 1.27
(95% CI: 1.07 - 1.52)
Crohn’s disease
122
90
212
OR: 1.13
(95% CI: 0.85 - 1.49)
Table 3 Surgery in IBD
Surgery in UC
Surgery in CD
·Resection: 8
Not operated: 86 (40.6 %)
·Proctocolectomy: 28
Operated: 126 (59.4 %)
- J Pouch: 25
·1 operation: 63 (29.7 %)
·2-3 operations: 50 (23.6 %)
·4-8 operations: 13 (6.1 %)
Table 4 Familial occurrence of IBD
Relationship
UC (n = 560)
CD (n = 212)
First-degree relative with IBD
17
15
Second-degree relative with IBD
2
6
Familial IBD
3.4 %
9.9%
Table 5 Smoking habits in IBD patients at presentation
UC n (%)
CD n (%)
Non-smoker
315 (67.3%)
87 (43.1%)
Ex-smoker
86 (18.4%)
13 (6.4%)
Smoker
67 (14.3%)
102 (50.5%)
No data
92
10
Odds ratio for smoking
0.25 (95% CI: 0.19 - 0.32)
1.94 (95% CI: 1.46 - 2.59)
Table 6 Colorectal carcinoma in IBD
Carcinomas
Age at diagnosis
Duration of IBD
Location of IBD
Location of tumor
UC (n = 10)
35 yrs
18.4 yrs
Pancolitis: 7
Ascending: 2
(20-56 yrs)
(9-33 yrs)
Left sided
Transverse: 4
colitis: 3
Descending: 2
Rectum: 2
CD (n = 2)
24 and 45 yrs
3 and 6 yrs
Right colon: 2
Transverse: 2
Citation: Lakatos L, Mester G, Erdelyi Z, Balogh M, Szipocs I, Kamaras G, Lakatos PL. Striking elevation in incidence and prevalence of inflammatory bowel disease in a province of western Hungary between 1977-2001. World J Gastroenterol 2004; 10(3): 404-409