Copyright
©The Author(s) 2004.
World J Gastroenterol. Nov 1, 2004; 10(21): 3146-3150
Published online Nov 1, 2004. doi: 10.3748/wjg.v10.i21.3146
Published online Nov 1, 2004. doi: 10.3748/wjg.v10.i21.3146
Table 1 Comparison of serum anti-H pylori IgG titers (mean ± SD) and grade of mucosal atrophy
Anti-H pylori IgG, EIU | |
No antral or corpus atrophy | 85.68 ± 17.81 |
No antral atrophy | 62.29 ± 12.02 |
Mild antral atrophy | 78.25 ± 5.86 |
Moderate antral atrophy | 74.08 ± 4.39 |
Severe antral atrophy | 73.38 ± 5.38 |
No corpus atrophy | 68.76 ± 8.35 |
Mild corpus atrophy | 77.21 ± 6.13 |
Moderate corpus atrophy | 76.47 ± 5.04 |
Severe corpus atrophy | 72.61 ± 4.72 |
Table 2 Comparison of serum PG1 and G17 levels (mean ± SD) and grade of IM
Table 3 Comparison of serum PG1 and G17 levels (mean ± SD) and the grade of dysplasia
Table 4 Correlations between results of different methods in diagnosis of gastric mucosal changes
Parameters | rs |
Detection of IM by endoscopy and histology | 0.41 |
Detection of IM by chromoendoscopy and histology | 0.92 |
Detection of antral atrophy by histology | -0.75 |
and serum levels of G-17 | |
Detection of corpus atrophy by histology | -0.71 |
and serum levels of PG-1 | |
Degree of stomach mucosal atrophy and IM | 0.21 |
Degree of stomach mucosal atrophy and dysplasia | 0.23 |
Degree of IM and dysplasia | 0.41 |
Table 5 Sensitivity (Se) and specificity (Sp), PPV and NPV of Biohit GastroPanel® in diagnosis of antral mucosal atrophy
Degree of antral atrophy | Se (%) | Sp (%) | PPV (%) | NPV (%) |
(by histology) | ||||
No | 83 | 95 | 53 | 99 |
Mild | 61 | 84 | 45 | 91 |
Moderate | 67 | 90 | 81 | 81 |
Severe | 89 | 99 | 98 | 94 |
Table 6 Sensitivity (Se) and specificity (Sp), PPV and NPV of Biohit GastroPanel® in diagnosis of corpus mucosal atrophy
Degree of corpus atrophy | Se (%) | Sp (%) | PPV (%) | NPV (%) |
(by histology) | ||||
No | 92 | 97 | 98 | 91 |
Mild | 71 | 92 | 48 | 97 |
Moderate | 72 | 96 | 81 | 93 |
Severe | 88 | 97 | 82 | 98 |
Table 7 Sensitivity (Se) and specificity (Sp), PPV and NPV of routine endoscopy and chromoendoscopy in diagnosis of in-testinal metaplasia (IM)
Routine endoscopy | Chromoendoscopy | |||||||
Se (%) | Sp (%) | PPV (%) | NPV (%) | Se (%) | Sp (%) | PPV (%) | NPV (%) | |
No | 98 | 6 | 35 | 86 | 94 | 99 | 98 | 97 |
Mild | 4 | 98 | 50 | 68 | 88 | 88 | 79 | 94 |
Moderate | no data | no data | no data | no data | 71 | 95 | 80 | 92 |
Severe | 6 | 99 | 33 | 89 | 82 | 98 | 82 | 98 |
- Citation: Pasechnikov VD, Chukov SZ, Kotelevets SM, Mostovov AN, Mernova VP, Polyakova MB. Possibility of non-invasive diagnosis of gastric mucosal precancerous changes. World J Gastroenterol 2004; 10(21): 3146-3150
- URL: https://www.wjgnet.com/1007-9327/full/v10/i21/3146.htm
- DOI: https://dx.doi.org/10.3748/wjg.v10.i21.3146