Expression of growth hormone and its receptor in chronic atrophic gastritis and its clinical significance

Table 1 Base-line characteristics of the patients

Characteristic	Group A	Group B	Group C
	(n = 30)	(n = 30)	(n = 30)
Age (yr)	48 ± 7	50 ± 6	52 ± 9
Male	19	17	20
Female	11	13	10
Endoscopical	normal gastric	chronic atrophic	gastric
finding	mucosa	gastritis(CAG)	cancer
Pathologic	mild superficial	moderate-severe	gastric
finding	gastritis(non-active)	CAG with or	cancer
		without intestinal
		malplasia

Table 2 Serum GH Level (ng/mL) in the studied groups (mean ± SD)

Group	A group	B group	C group
	(n = 30)	(n = 30)	(n = 30)
GH level	2.869 ± 0.5121,2	1.021 ± 0.1321	3.176 ± 0.4212

¹t_AB = 3.135 P < 0.01 ¹t_BC = 3.537 P < 0.01

²t_AC = 1.893 P > 0.05.

Table 3 Positive rate of gastric mucosal GHR expression in the studied groups (%)

Group	A group	B group	C group
	(n = 30)	(n = 30)	(n = 30)
GHR expression	100 (30/30)1	10 (3/30)2	13 (4/30)1,2

¹χ²_AB = 49 P < 0.01 ¹χ²_AC = 45 P < 0.01

²χ²_BC = 0.16 P > 0.05.