Effect of traditional Chinese medicinal enemas on ulcerative colitis of rats

Table 1 Expression of colonic mucosal cytokines in MG and RG before therapy (mean ± SD)

Group	n	IL-6 (U/mL)	TNF-α (ng/L)	IFN-γ (ng/L)
Model	8	38.29 ± 2.61b	16.54 ± 1.23 b	8.61 ± 0.89 b
Control	8	31.56 ± 2.47	12.81 ± 1.38	5.28 ± 0.56

^bP < 0.01 vs control group.

Table 2 Comparison between expressions of colonic lympho-cyte surface adhesive molecules (mean ± SD, %)

Group	n	CD4+CD11a+	CD4+CD18+	CD8+CD11a+	CD8+CD18+
Model	8	29.81 ± 1.17	26.24 ± 1.12	13.51 ± 2.31a	12.22 ± 1.13a
Control	8	29.70 ± 1.36	26.89 ± 1.26	16.68 ± 1.41	16.79 ± 1.11

^aP < 0.05 vs control group.

Table 3 Changes of colonic mucosal cytokines after therapy (n = 10, mean ± SD)

Group	IL-6 (U/mL)	TNF-α (ng/L)	IFN-γ (ng/L)
GI	32.48 ± 2.53a,e	13.42 ± 1.57a,e	5.87 ± 0.84a,e
GII	34.56 ± 3.21c	14.81 ± 1.48c	6.36 ± 0.62c
GIII	37.32 ± 2.54	16.13 ± 1.36	8.21 ± 0.77
GIV	31.16 ± 2.19	12.71 ± 1.51	5.35 ± 0.63

^aP > 0.05,

^cP < 0.05 vs GIV;

^eP < 0.05 vs GII.

Table 4 Expression of colonic mucosal lymphoid T surface adhesive molecules (n = 10, mean ± SD)

Group	CD4+CD11a+ (%)	CD4+CD18+ (%)	CD8+CD11a+ (%)	CD8+CD18+ (%)
GI	27.51 ± 1.13	25.23 ± 1.45	16.01 ± 1.05a,e	16.28 ± 0.19a,e
GII	27.35 ± 1.23	25.54 ± 1.50	13.16 ± 1.34c	13.27 ± 1.44c
GIII	27.42 ± 1.56	25.51 ± 1.28	11.52 ± 1.29	11.34 ± 1.61
GIV	27.61 ± 1.43	25.45 ± 1.26	16.45 ± 1.23	16.56 ± 1.13

^aP > 0.05,

^cP < 0.05 vs GIV;

^eP < 0.05 vs GII.