Intestinal microecology and quality of life in irritable bowel syndrome patients

Table 1 Enteric symptom scales

Symptoms	0	1	2	3
Duration of abdominal pain (h/d)	None	< 1	2-8	> 8
Frequency of abdominal pain (d/wk)	None	1-2	3-5	6-7
Ratio of abnormal shape of stool	None	< 1/4	1/4-3/4	> 3/4
Ratio of abnormal passage of defecation	None	< 1/4	1/4-3/4	> 3/4
Ratio of mucous stool	None	< 1/4	1/4-3/4	> 3/4
Distention or gastrectasia when defecation	None	< 1/4	1/4-3/4	> 3/4

Table 2 Number of bacteria and B/E value in two groups (mean ± SD, LgN/g stool)

Bacteria (%)	IBS patients (n = 25)	Controls(n = 25)
Lactobacillus	6.79 ± 1.73 (92)	6.79 ± 1.94 (84)
Bifidobacteriaa	8.14 ± 2.14 (96)	9.32 ± 1.22 (100)
Bacteroides	10.49 ± 0.56 (100)	10.62 ± 0.79 (100)
C.perfringensd	7.32 ± 2.12 (40)	6.66 ± 1.68 (80)
Enterococus	7.96 ± 1.53 (100)	7.49 ± 1.29 (100)
Enterobacteriaceaea	9.02 ± 1.04 (100)	8.44 ± 0.95 (100)
B/E valueb	0.91 ± 0.27 (96)	1.12 ± 0.23 (100)

The data in the bracket mean positive rate (This is applicable for the following tables including flora.).

^aP < 0.05 flora vs control,

^bP < 0.01 B/E value vs control,

^dP < 0.01 detection frequency vs control.

Table 3 Number of bacteria and B/E value in younger sub-group and elder subgroup in IBS group (mean ± SD, LgN/g stool)

Bacteria (%)	Younger subgroup (n = 12)	Elder subgroup (n = 13)
Lactobacillus	6.63 ± 1.83 (100)	6.98 ± 1.70 (84)
Bifidobacteria	7.60 ± 2.65 (100)	8.68 ± 1.38 (92)
Bacteroides	10.52 ± 0.42 (100)	10.47 ± 0.72 (100)
C.perfringens	8.84 ± 1.07 (25)	6.89 ± 2.20 (54)
Enterococus	8.26 ± 1.58 (100)	7.69 ± 1.50 (100)
Enterobacteriaceae	9.16 ± 1.22 (100)	8.90 ± 0.88 (100)
B/E value	0.85 ± 0.33 (100)	0.98 ± 0.19 (92)

Table 4 Number of bacteria and B/E value in younger subgroup and elder subgroup of control group. (mean ± SD, LgN/g stool)

Bacteria (%)	Younger subgroup (n = 12)	Elder subgroup (n = 13)
Lactobacillus	6.18 ± 2.07 (75)	7.20 ± 1.83 (92)
Bifidobacteria	9.32 ± 1.08 (100)	9.32 ± 1.38 (100)
Bacteroides	10.49 ± 0.71 (100)	10.75 ± 0.89 (100)
C.perfringens	6.45 ± 1.82 (83)	6.89 ± 1.59 (77)
Enterococus	7.09 ± 1.49 (100)	7.86 ± 1.00 (100)
Enterobacteriaceae	8.05 ± 1.14 (100)	8.81 ± 0.57 (100)
B/E value	1.19 ± 0.28 (100)	1.06 ± 0.14(100)

^aP < 0.05 flora vs control.

Table 5 QoL of IBS patients and normal control (mean ± SD)

QoL scale	IBS patients (n = 25)	Controls (n = 25)
PF	74.40 ± 26.78	85.40 ± 15.53
RPa	52.00 ± 44.44	77.00 ± 37.44
BPb	73.33 ± 17.57	84.89 ± 16.00
GHb	41.40 ± 15.04	73.40 ± 13.52
VTb	53.40 ± 16.94	69.60 ± 17.38
SFb	75.00 ± 12.50	84.50 ± 12.12
REb	61.33 ± 41.59	96.00 ± 11.06
MHb	58.24 ± 16.21	80.00 ± 13.52

^aP < 0.05 ,

^bP < 0.01 vs healthy control.

Table 6 Correlation between enteric symptoms and QoL in IBS (mean ± SD)

	Score of QoL	Score of enteric	Correlation
		symptoms	coefficient (r)
PF	74.40 (26.78)	7.56 (2.31)	-0.062
RP	52.00 (44.44)	7.56 (2.31)	0.060
BP	73.33 (17.57)	7.56 (2.31)	-0.347
GH	41.40 (15.04)	7.56 (2.31)	-0.137
VT	53.40 (16.94)	7.56 (2.31)	-0.280
SF	75.00 (12.50)	7.56 (2.31)	0.018
RE	61.33 (41.59)	7.56 (2.31)	-0.257
MH	58.24 (16.21)	7.56 (2.31)	0.001