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©The Author(s) 2004.
World J Gastroenterol. Jun 15, 2004; 10(12): 1750-1754
Published online Jun 15, 2004. doi: 10.3748/wjg.v10.i12.1750
Published online Jun 15, 2004. doi: 10.3748/wjg.v10.i12.1750
Table 1 Baseline characteristics of patients with non-ulcer dyspepsia (NUD)
| Charateristics | Controls (n = 17) | All NUD pts (n = 33) | Hp positive NUD pts (n = 23) | Hp negative NUD pts (n = 10) |
| Sex (Male:Female) | 9:8 | 20:13 | 13:10 | 7:3 |
| Age (yr) (mean ± SD) | 27.7 ± 6.7 | 37.3 ± 14.5 | 39.3 ± 14.2 | 35.2 ± 18.4 |
| Body mass (kg) (mean ± SD) | 66.6 ± 13.8 | 74.3 ± 10.0 | 75.6 ± 9.8 | 71.2 ± 10.1 |
| Hp(+) (%) | 9 (52.9) | 23 (69.7) | 23 (100) | 0 (0) |
| Smokers (%) | 8 (47.1) | 10 (30.3) | 7 (30.4) | 3 (30) |
Table 2 Gastric emptying: H pylori-positive NUD patients vs H pylori-negative NUD patients
| parameters (mean ± SD, M) | Hp positiveNUD pts (n = 23) | Hp negative NUD pts (n = 10) | Mann-Whitney U test | 95% CI for difference between |
| medians (Hp pos. -Hp neg.) | ||||
| Cmax/BM (mg/L·kg) | 0.172 ± 0.070 (0.153) | 0.177 ± 0.050 (0.176) | P = 0.58 | -0.050 to 0.037 |
| AUC/BM (mg·min/L·kg) | 18.43 ± 6.93 (18.53) | 18.38 ± 5.94 (19.42) | P = 0.91 | -5.36 to 4.62 |
Table 3 Gastric emptying: NUD patients vs asymptomatic controls
| parameters (mean ± SD, M) | NUD pts (n = 33) | Controls (n = 17) | Mann-Whitney U test | 95% CI for difference between |
| medians (NUD pts-Controls) | ||||
| Cmax/BM (mg/L·kg) | 0.173 ± 0.064 (0.163) | 0.224 ± 0.076 (0.221) | P = 0.02 | -0.012 to-0.095 |
| AUC/BM (mg·min/L·kg) | 18.42 ± 6.56 (18.53) | 24.34 ± 8.06 (25.53) | P = 0.01 | -2.11 to-10.93 |
Table 4 Gastric emptying: H pylori-positive NUD patients before and after eradication (intra-individual comparisons)
| Parameters (mean ± SD, M) | Initially Hp positive NUD pts (n = 14) | Wilcoxon matched pairs test | 95%CI for the median | |
| Before eradication | After eradication | difference (after-before) | ||
| Cmax/BM (mg/L·kg) | 0.171 ± 0.074 (0.167) | 0.160 ± 0.064 (0.146) | P = 0.64 | -0.047 to 0.278 |
| AUC/BM (mg·min/L·kg) | 17.41 ± 5.25 (18.95) | 18.02 ± 7.25 (16.88) | P = 0.93 | -3.04 to 4.38 |
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Citation: Leontiadis GI, Minopoulos GI, Maltezos E, Kotsiou S, Manolas KI, Simopoulos K, Hatseras D. Effects of
Helicobacter pylori infection on gastric emptying rate in patients with non-ulcer dyspepsia. World J Gastroenterol 2004; 10(12): 1750-1754 - URL: https://www.wjgnet.com/1007-9327/full/v10/i12/1750.htm
- DOI: https://dx.doi.org/10.3748/wjg.v10.i12.1750