Efficacy and safety of modified tetracycline dosing in a quadruple therapy for Helicobacter pylori: A retrospective single center study

Table 2 Treatment times previously of the enrolled patients and its eradication rates

Treatment times	500 mg b.i.d.	750 mg b.i.d.	500 mg t.i.d.
1	93.4% (127/136)	97.5% (77/79)	92.6% (87/94)
2	83.3% (15/18)	87.5% (28/32)	90.9% (20/22)
≥ 3	100% (3/3)	71.4% (5/7)	100% (3/3)
Rescue therapy1	85.7% (18/21)	84.6% (33/39)	92.0% (23/25)

¹Rescue therapy was defined as patients who had eradicated therapy once or more but failed.

500 mg b.i.d.: Tetracycline twice daily; 750 mg b.i.d.: Tetracycline twice daily; 500 mg t.i.d.: Tetracycline three times daily.