Acquired amegakaryocytic thrombocytopenia previously diagnosed as idiopathic thrombocytopenic purpura in a patient with hepatitis C virus infection

Figure 2 Macroscopic and histopathological features of autopsy specimens. A: The cut surface of the liver shows diffuse micronodular cirrhosis with a yellow-green lesion in the right lobe; B: The non-tumorous liver shows diffuse small regenerative nodules with fibrous septum (Elastica-Goldner staining, scale bar; 1000 μm); C and D: Histopathological findings of combined hepatocellular-cholangiocarcinoma; C: hepatocellular carcinoma component (H and E staining) and D: adenocarcinoma component (Alcian Blue-Periodic Acid Schiff staining) (C and D, scale bar; 200 μm); E: In the bone marrow, no megakaryocytes are observed (H and E staining); F: A small megakaryocyte is identified through immunostaining for CD41 (E and F, scale bar; 100 μm).