Intestinal microbiota and type 2 diabetes: From mechanism insights to therapeutic perspective

doi:10.3748/wjg.v20.i47.17737

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 21, 2014; 20(47): 17737-17745
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17737

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Figure 2 Role of the intestinal microbiota in the pathogenesis of type 2 diabetes. The intestinal microbiota may play an important role in the onset of type 2 diabetes by influencing body weight, bile acid metabolism, proinflammatory activity, NAFLD and insulin resistance, and modulating gut hormones. NAFLD: Non-alcoholic fatty liver disease; SCFAs: Short-chain fatty acids; FXR: Farnesoid X receptor; GLP: Glucagon-like peptide; PYY: Peptide YY.

Citation: Han JL, Lin HL. Intestinal microbiota and type 2 diabetes: From mechanism insights to therapeutic perspective. World J Gastroenterol 2014; 20(47): 17737-17745
URL: https://www.wjgnet.com/1007-9327/full/v20/i47/17737.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i47.17737