Optimized management of advanced hepatocellular carcinoma: Four long-lasting responses to sorafenib

Figure 1 Patient 4 - arterial phase computed tomography scans. A: Pre-sorafenib, the 25-mm lesion in segment VIII was biopsied, and measured > 100 HU. B: Partial response, tumor necrosis and intra-lesional HU of 40-70 after 4 mo on sorafenib. C: After 40 mo on sorafenib, the necrotic area measured < 40 HU intra-lesionally, and was disease-free at histological examination. The arrows show the liver lesion.