Impaired PI3K/Akt signal pathway and hepatocellular injury in high-fat fed rats

doi:10.3748/wjg.v16.i48.6111

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Dec 28, 2010 (publication date) through Jan 22, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 28, 2010; 16(48): 6111-6118
Published online Dec 28, 2010. doi: 10.3748/wjg.v16.i48.6111

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Figure 5 Simulation diagram of the relationship between insulin signaling pathway and hepatocyte apoptosis. PI3K: Phosphatidylinositol 3-kinase; Akt: Protein kinase B; BAD: Bcl2-associated agonist of cell death; MEK: Mitogen-activated protein kinase kinase; clAP-1: Cell inhibitors of apoptosis protein-1; Cyt C: Cytochrome c; APAF: Apoptotic peptidase activating factor.

Citation: Han JW, Zhan XR, Li XY, Xia B, Wang YY, Zhang J, Li BX. Impaired PI3K/Akt signal pathway and hepatocellular injury in high-fat fed rats. World J Gastroenterol 2010; 16(48): 6111-6118
URL: https://www.wjgnet.com/1007-9327/full/v16/i48/6111.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i48.6111