Thiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease

doi:10.3748/wjg.v16.i25.3187

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Jul 7, 2010 (publication date) through Jan 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2010; 16(25): 3187-3195
Published online Jul 7, 2010. doi: 10.3748/wjg.v16.i25.3187

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Figure 2 Association between thiopurine S-methyltransferase (TPMT) polymorphisms and all adverse drug reactions (ADRs) (A), bone marrow toxicity (B), hepatotoxicity (C) and pancreatitis (D). Total: Total number of patients within the ADRs or no ADRs group; Events: Number of patients with one or more TPMT alleles within the ADRs or no ADRs group. neg assoc: Favoured the no ADRs group; pos assoc: Favoured the ADRs group.

Citation: Dong XW, Zheng Q, Zhu MM, Tong JL, Ran ZH. Thiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease. World J Gastroenterol 2010; 16(25): 3187-3195
URL: https://www.wjgnet.com/1007-9327/full/v16/i25/3187.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i25.3187