Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury

doi:10.3748/wjg.v16.i11.1366

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Mar 21, 2010 (publication date) through Jan 30, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2010; 16(11): 1366-1376
Published online Mar 21, 2010. doi: 10.3748/wjg.v16.i11.1366

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Figure 2 Proposed mechanism by which SAM protects against CYP2e1-hepatotoxicity. ROS: Reactive oxygen species; CYP: Cytochrome P450; NF-κB: Nuclear factor κB; Nrf2: Nuclear factor erythroid 2-related factor 2.

Citation: Cederbaum AI. Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury. World J Gastroenterol 2010; 16(11): 1366-1376
URL: https://www.wjgnet.com/1007-9327/full/v16/i11/1366.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i11.1366