Inhibition of conjugated linoleic acid on mouse forestomach neoplasia induced by benzo (a) pyrene and chemopreventive mechanisms

Figure 1 The establishment of mouse neoplasia model induced by B (a) P. (A): normal forestomach; (B, C): forestomach neoplasia.

Figure 2 The pathological analysis of mouse forestomach. (A): normal forestomach × 10; (B): Atypical hyperplasia × 10; (C): Carci-noma in situ× 4.

Figure 3 Apoptosis induced by CLA in mice forestomach. (A or B): there were few apoptotic cells in group A and B; (C): the apoptosis induced by CLA. Arrow showed apoptotic cells × 40.

Figure 4 The effect of CLA on the expression of MEK-1 protein.

Figure 5 The effect of CLA on the expression of ERK-1 protein.

Figure 6 The effect of CLA on the expression of MKP-1 protein.