Expression changes of activin A in the development of hepatic fibrosis

Figure 1 Fake lobuli formed after CCl₄ was injected for 7 weeks. VG staining, × 100

Figure 2 Normal rat liver activin βA immunostaining, immunoreactivity was detected in hepatocytes. DAB, × 100

Figure 3 Activin β A immunostaining after 3-week CCl₄ injections. DAB, × 400

Figure 4 Hepatocytes around connective septa were detected by immunostaining after 7 weeks’ CCl₄ treatment. DAB, × 200

Figure 5 Hepatocytes around central veins by activin β immunostaining after 7-weeks CCl₄ treatment. DAB, × 400

Figure 6 The mRNA expression of activin A at the different stages of CCl₄ induced hepatic fibrosis. N: normal, W: week, M: marker

Figure 7 A relative amount of activin βA mRNA were quantified using an image analyzer. ^aP < 0.01 vs N; ^bP < 0.01 vs 4 w; ^cP < 0.05 vs 4 w. N: normal group, W: week