Effects of Taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2

Figure 1 Reverse transcription-polymerase chain reaction (RT-PCR) analysis of drug resistance gene messenger RNA mdr1 in SUIT-2 and S2/TXT cell lines. RT-PCR was performed with 30 cycles of PCR amplification. The β-actin gene RT-PCR products confirms that intact mRNA is equally present in each of the cell lines. This figure shows that there were strong expressions of mdr1 in TXT-resistant cell line S2/TXT and SUIT-2 cells treated with 0.4 nM TXT for 24 h, no expressions in the parental cell line SUIT-2. Metastasis-related gene expressions had no difference in these cells.