Basic Study
Copyright ©The Author(s) 2025.
World J Gastroenterol. Mar 7, 2025; 31(9): 103188
Published online Mar 7, 2025. doi: 10.3748/wjg.v31.i9.103188
Figure 1
Figure 1 Experimental design. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; γ-GT: Gamma-glutamyltransferase; Total bilirubin; POD3: Postoperative day 3.
Figure 2
Figure 2 Schematic representation of an extended-criteria donor autologous orthotopic liver transplantation. PV: Portal vein; SHVC: Suprahepatic vena cava; IHVC: infrahepatic vena cava.
Figure 3
Figure 3 Rat autologous orthotopic liver transplantation. A: The liver graft was cold flushed through the portal vein and hepatic artery with Lactated Ringer’s solution; B: Restoration of the liver graft blood flow.
Figure 4
Figure 4 Color and near-infrared fluorescence images of liver grafts at different time points after the anhepatic period.
Figure 5
Figure 5 Survival rate (postoperative day 3), near-infrared fluorescence curve, and liver function (postoperative day 3). A: Near-infrared fluorescence curves; B: Near-infrared fluorescence curve growth rates; C: Survival rates; D: Serum aspartate aminotransferase levels; E: Serum alanine aminotransferase levels; F: Serum alkaline phosphatase levels; G: Serum gamma-glutamyltransferase levels; H: Serum total bilirubin levels. aP < 0.05 vs control group; bP < 0.01 vs control group; cP < 0.05 vs 0-minute group; dP < 0.01 vs 0-minute group; eP < 0.05 vs 10-minute group; gP < 0.05 vs 20-minute group. FI: Fluorescence imaging; POD 3: Postoperative day 3; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; γ-GT: Gamma-glutamyltransferase; TBIL: Total bilirubin.
Figure 6
Figure 6 Histological evaluations of the liver grafts. A: Representative hematoxylin and eosin and immunofluorescence (CK7 and CD31) staining of the liver grafts; B: Suzuki score; C: Bile duct epithelium cell (CK7+) count; D: Microvascular density quantification (CD31+). aP < 0.05 vs control group; bP < 0.01 vs control group; cP < 0.05 vs 0-minute group; dP < 0.01 vs 0-minute group; fP < 0.01 vs 10-minute group.