Impact of baseline body mass index on the long-term prognosis of advanced hepatocellular carcinoma treated with immunotherapy

Figure 1 Flow diagram depicting the patients with infiltrative hepatocellular camrelizumab enrolled in the study. PD1: Programmed cell death protein 1; BMI: Body mass index.

Figure 2 Graph depicting the effect of different body mass index values on long-term survival of patients and further subgroup analysis. A: Kaplan-Meier plot of in the body mass index (BMI) ≤ 25 kg/m² and BMI > 25 kg/m² groups; B: Kaplan-Meier plot of overall survival in the BMI ≤ 25 kg/m² and BMI > 25 kg/m² groups; C: Kaplan-Meier plot of analysis of progression-free survival subgroup by BMI; D: Kaplan-Meier plot of analysis of the overall survival subgroup by BMI. BMI: Body mass index; HR: Hazard ratio; CI: Confidence interval.

Figure 3 Graph depicting the prognostic model for predicting 9-, 12-, and 18-month overall survival. BCLC: Barcelona Clinic Liver Cancer; PVTT: Portal vein tumor thrombus; BMI: Body mass index; AFP: Alpha-fetoprotein; OS: Overall survival.

Figure 4 Graph depicting the operating characteristic evaluation plot for a prognostic model. A: Graph showing the training set receiver operating characteristic (ROC) evaluation plot for 9-month prognostic prediction model; B: Graph showing the validation set ROC evaluation plot for 9-month prognostic prediction model; C: Graph showing the training set ROC evaluation plot for 12-month prognostic prediction model; D: Graph showing the validation set ROC evaluation plot for 12-month prognostic prediction model; E: Graph showing the training set ROC evaluation plot for the 18-month prognostic prediction model; F: Graph showing the validation set ROC evaluation plot for the 18-month prognostic prediction model. AUC: Area under the receiver operating characteristic curve.

Figure 5 Graph illustrating the calibration plots for a prognostic model. A: Calibration plots for the training set 9-month overall survival (OS); B: Calibration plots for the validation set 9-month OS; C: Calibration plots for the training set 12-month OS; D: Calibration plots for the validation set 12-month OS; E: Calibration plots for the training set 18-month OS; F: Calibration plots for validation set 18-month OS.