Success of susceptibility-guided eradication of Helicobacter pylori in a region with high secondary clarithromycin and levofloxacin resistance rates

doi:10.3748/wjg.v30.i2.184

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Jan 14, 2024 (publication date) through Jul 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2024; 30(2): 184-195
Published online Jan 14, 2024. doi: 10.3748/wjg.v30.i2.184

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Figure 1 Secondary resistance rate of Helicobacter pylori strains to clarithromycin and levofloxacin.

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Figure 2 Flow diagram of antibiotic-susceptibility-guided therapy. qPCR: Quantitative polymerase chain reaction; UBT: Urea Breath Test; ITT: Intention-to-treat; PP: Per-protocol; A: Amoxicillin; B: Bismuth; C: Clarithromycin; F: Furazolidone; L: Levofloxacin; MH: Minocycline hydrochloride; P: Proton pump inhibitor; CLA^R: Clarithromycin-resistant; CLA^S: Clarithromycin-susceptible; LFX^R: Levofloxacin-resistant; LFX^S: Levofloxacin-susceptible.

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Figure 3 Empiric eradication treatment regimens of Helicobacter pylori infection. UBT: Urea Breath Test; ITT: Intention-to-treat; PP: Per-protocol; A: Amoxicillin; B: Bismuth; C: Clarithromycin; F: Furazolidone; L: Levofloxacin; MH: Minocycline hydrochloride; P: Proton pump inhibitor.

Citation: Wang YM, Chen MY, Chen J, Zhang XH, Feng Y, Han YX, Li YL. Success of susceptibility-guided eradication of Helicobacter pylori in a region with high secondary clarithromycin and levofloxacin resistance rates. World J Gastroenterol 2024; 30(2): 184-195
URL: https://www.wjgnet.com/1007-9327/full/v30/i2/184.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i2.184