Interplay between metabolic dysfunction-associated fatty liver disease and renal function: An intriguing pediatric perspective

doi:10.3748/wjg.v30.i15.2081

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 21, 2024; 30(15): 2081-2086
Published online Apr 21, 2024. doi: 10.3748/wjg.v30.i15.2081

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Figure 1 The complex pathophysiological interplay between metabolic (dysfunction) associated fatty liver disease and renal function. T2D: Type 2 diabetes; FFA: Free fatty acids; MAFLD: Metabolic (dysfunction) associated fatty liver disease; CKD: Chronic kidney disease; ROS: Reactive oxygen species; RNS: Reactive nitrogen species; SCFAs: Short chain fatty acids; TMAOs: Trimethylamine-N-oxides; PNPLA3: Patatin-like phospholipase domain-containing 3; TM6SF2: Transmembrane 6 superfamily member 2; MBOAT7: Membrane-bound O-acyltransferase 7.

Citation: Nardolillo M, Rescigno F, Bartiromo M, Piatto D, Guarino S, Marzuillo P, Miraglia del Giudice E, Di Sessa A. Interplay between metabolic dysfunction-associated fatty liver disease and renal function: An intriguing pediatric perspective. World J Gastroenterol 2024; 30(15): 2081-2086
URL: https://www.wjgnet.com/1007-9327/full/v30/i15/2081.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i15.2081