Survival benefit of younger gastric cancer patients in China and the United States: A comparative study

Figure 1 The ratio of younger patients with gastric cancer based on the China National Cancer Center and Surveillance Epidemiology and End Results databases from 2000 to 2018.

Figure 2 The survival trends of younger patients with gastric cancer based on the China National Cancer Center and Surveillance Epidemiology and End Results databases. A: Trends of the 3-year overall survival; B: Trends of the 5-year overall survival.

Figure 3 Kaplan-Meier survival curves of different regions and races from the China National Cancer Center and Surveillance Epidemiology and End Results databases from 2000 to 2018. A: All gastric cancer; B: Gastric cancer diagnosed as Tumor-Node-Metastasis (TNM) stage I; C: Gastric cancer diagnosed as TNM stage II; D: Gastric cancer diagnosed as TNM stage III; E: Gastric cancer diagnosed as TNM stage IV.

Figure 4 Prognostic nomogram for younger gastric cancer patients. A: Nomogram based on the China National Cancer Center; B: Nomogram based on the Surveillance Epidemiology and End Results database. ELN: Examined lymph nodes; pTNM: Pathological Tumor-Node-Metastasis.

Figure 5 After differentially expressed genes analysis was performed among different regional sets, 50 significant differently expressed genes were selected. A: Heatmap constructed with the differentially expressed genes for younger gastric cancer patients; B: Protein–protein interaction network; C: Top 10 hub genes with higher degree of connectivity.