Location-based prediction model for Crohn’s disease regarding a novel serological marker, anti-chitinase 3-like 1 autoantibodies

Figure 1 Kaplan-Meier survival analysis for the probability of internal penetrating/stricturing complication development in Crohn’s disease patients with non-stricturing and non-penetrating disease at diagnosis. A: Comparing survival curves of immunoglobulin A (IgA)-type anti-CHI3L1 autoantibody (aCHI3L1) positive vs negative subgroups; B: Comparing survival curves of secretory IgA-type aCHI3L1 positive vs negative subgroups. IP/S: Internal penetrating/stricturing; NSNP: Non-stricturing and non-penetrating; IgA: Immunoglobulin A; sIgA: Secretory immunoglobulin A; aCHI3L1: Anti-CHI3L1 autoantibodies.

Figure 2 Kaplan-Meier survival analysis for the probability of internal penetrating/stricturing complication development in Crohn’s disease patients with non-stricturing and non-penetrating disease and colonic involvement at diagnosis. A: Comparing survival curves of immunoglobulin A (IgA)-type anti-CHI3L1 autoantibody (aCHI3L1) positive vs negative subgroups; B: Comparing survival curves of secretory IgA-type aCHI3L1 positive vs negative subgroups. IP/S: Internal penetrating/stricturing; NSNP: Non-stricturing and non-penetrating; IgA: Immunoglobulin A; sIgA: Secretory immunoglobulin A; CHI3L1: Chitinase 3-like 1.