Retrospective Study
Copyright ©The Author(s) 2022.
World J Gastroenterol. Feb 28, 2022; 28(8): 853-867
Published online Feb 28, 2022. doi: 10.3748/wjg.v28.i8.853
Figure 1
Open in New Tab Full Size Figure Download Figure
Figure 1 Flow diagram of the study enrollment. GERD: Gastroesphageal reflux disease; GI: Gastrointestinal; NERD: Non-erosive reflux disease; PPI: Proton pump inhibitor; LA: Los Angeles.
Figure 2
Open in New Tab Full Size Figure Download Figure
Figure 2 Multivariate analysis on the risk for occurrence of gastroesphageal reflux disease according to the extent of endoscopic atrophic gastritis. 1Adjusted for age, sex, body mass index, metabolic syndrome, medication of sedatives or hypnotics, alcohol consumption, smoking history, physical activity, dietary factor, and Helicobacter pylori immunoglobulin G. CI: Confidence interval; GERD: Gastroesophageal reflux disease; OR: Odds ratio.
Figure 3
Open in New Tab Full Size Figure Download Figure
Figure 3 The grade of gastroesophageal reflux disease in relation to the extent of endoscopic atrophic gastritis. A: Prevalence of gastroesophageal reflux disease (GERD) according to the extent of endoscopic atrophic gastritis (EAG); B: Distribution of the severity of GERD according to the extent of EAG. NERD: Non-erosive reflux disease; LA: Los Angeles.
Figure 4
Open in New Tab Full Size Figure Download Figure
Figure 4 Impact of the extent of endoscopic atrophic gastritis on the risk for severity of gastroesophageal reflux disease. 1Adjusted for age, sex, body mass index, metabolic syndrome, medication of sedatives or hypnotics, alcohol consumption, smoking history, physical activity, dietary factor, and Helicobacter pylori immunoglobulin G. NERD: Non-erosive reflux disease; CI: Confidence interval; OR: Odds ratio; LA: Los Angeles.
Figure 5
Open in New Tab Full Size Figure Download Figure
Figure 5 Pepsinogen I, II and I/II ratio according to the severity of gastroesophageal reflux disease. aP < 0.0033 compared to normal; bP < 0.001 compared to non-erosive reflux disease. NERD: Non-erosive reflux disease; LA: Los Angeles.
Figure 6
Open in New Tab Full Size Figure Download Figure
Figure 6 Prevalence of gastroesophageal reflux disease according to serologic atrophic gastritis. NERD: Non-erosive reflux disease; LA: Los Angeles; SAG: Serologic atrophic gastritis.
Figure 7
Open in New Tab Full Size Figure Download Figure
Figure 7 Multivariate analysis on the risk for occurrence of gastroesophgeal reflux disease according to serologic atrophic gastritis. 1Adjusted for age, sex, body mass index, metabolic syndrome, medication of sedatives or hypnotics, alcohol consumption, smoking history, physical activity, dietary factor, and Helicobacter pylori immunoglobulin G Ab. NERD: Non-erosive reflux disease; CI: Confidence interval; SAG: Serologic atrophic gastritis; OR: Odds ratio.