Prevalence and clinical characteristics of autoimmune liver disease in hospitalized patients with cirrhosis and acute decompensation in China

Figure 1 Flow chart of the study. AD: Acute decompensation; AILD: Autoimmune liver disease; ACLF: Acute-on-chronic liver failure.

Figure 2 Distribution and the number of autoimmune liver disease patients enrolled from each of center and from Renji Hospital. A: District distribution of each enrolled center; B: The number of patients enrolled from center; C: Population distribution of patients from Renji Hospital; D: The number of patients enrolled from each of the 20 districts. Approximately 94% of the total Chinse population resides east of the dividing line (Hu Line) in the figure, and 6% resides west of the line; 13 centers lie in eastern China, and 1 lies in western China.

Figure 3 Outcomes of autoimmune liver disease patients with acute decompensated cirrhosis and acute-on-chronic liver failure. A: Liver transplantation (LT)-free mortality in patients with cirrhosis and acute decompensation; B: LT-free mortality in patients with acute-on-chronic liver failure. LT: Liver transplantation; PBC: Primary biliary cirrhosis; AIH: Autoimmune hepatitis; PBC/AIH: Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome; AD: Acute decompensation; ACLF: Acute-on-chronic liver failure.

Figure 4 Multivariate analysis of 90-d liver transplantation free mortality in autoimmune liver disease patients with cirrhosis and acute decompensation. OR: Odds ratio; CI: Confidence interval.