Risk of hepatitis B virus reactivation in patients with autoimmune diseases undergoing non-tumor necrosis factor-targeted biologics

doi:10.3748/wjg.v27.i19.2312

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May 21, 2021 (publication date) through Nov 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 21, 2021; 27(19): 2312-2324
Published online May 21, 2021. doi: 10.3748/wjg.v27.i19.2312

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Figure 1 The possible immunological mechanism to explain how non-tumor necrosis factor-targeted biologics can induce the development of hepatitis B reactivation. cccDNA: Covalently closed circular DNA; HBV: Hepatitis B virus; IFN: Interferon; IL: Interleukin; T_H17 cells: IL-17 producing T helper cells; T_H1 cells: T helper 1 cells; Tc cells: Cytotoxic T cells.

Citation: Akiyama S, Cotter TG, Sakuraba A. Risk of hepatitis B virus reactivation in patients with autoimmune diseases undergoing non-tumor necrosis factor-targeted biologics. World J Gastroenterol 2021; 27(19): 2312-2324
URL: https://www.wjgnet.com/1007-9327/full/v27/i19/2312.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i19.2312