Factors influencing the failure of interferon-free therapy for chronic hepatitis C: Data from the Polish EpiTer-2 cohort study

Figure 1 Patient disposition and treatment outcomes. SVR: Sustained virologic response.

Figure 2 Distribution of treatment regimens among patients who did and did not achieve sustained virologic response. SVR: Sustained virologic response; RBV: Ribavirin; SOF: Sofosbuvir; PrOD: Paritaprevir/ritonavir +/- dasabuvir; LDV: Ledipasvir; GZR: Grazoprevir; EBR: Elbasvir; GLE: Glecaprevir; PIB: Pibrentasvir; VEL: Velpatasvir; ASV: Asunaprevir; DCV: Daclatasvir.

Figure 3 Prediction accuracy and the value of Cohen's κ statistic for individual machine learning algorithms. cart: Classification and regression tree; knn: K-nearest neighbors; svm: Support vector machine; rf: Random forest.

Figure 4 The receiver operating characteristic curve showing the accuracy of the final model for the test data.

Figure 5 The most important factors influencing treatment failure: mean accuracy decrease. HCV: Hepatitis C virus; INR: International normalized ratio; BMI: Body mass index; PLT: Platelets; ALT: Alanine aminotransferase; MELD: Model for End-stage Liver Disease.

Figure 6 The most important factors influencing treatment failure: mean Gini coefficient decrease. HCV: Hepatitis C virus; INR: International normalized ratio; BMI: Body mass index; PLT: Platelets; ALT: Alanine aminotransferase; MELD: Model for End-stage Liver Disease.