How far along are we in revealing the connection between metformin and colorectal cancer?

doi:10.3748/wjg.v27.i14.1362

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Apr 14, 2021 (publication date) through Nov 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2021; 27(14): 1362-1368
Published online Apr 14, 2021. doi: 10.3748/wjg.v27.i14.1362

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Figure 1 Metformin mode of action including chemopreventive potential in colorectal cancer development. CRC: Colorectal cancer; NF-kB: Nuclear factor kB; AMPK: Adenosine monophosphate-activated protein kinase; GSK3β: Glycogen synthase kinase-3β; PPAR-γ: Proliferator-activated receptor-γ; mTOR: Mechanistic target of rapamycin.

Citation: Berkovic MC, Mikulic D, Bilic-Curcic I, Mrzljak A. How far along are we in revealing the connection between metformin and colorectal cancer? World J Gastroenterol 2021; 27(14): 1362-1368
URL: https://www.wjgnet.com/1007-9327/full/v27/i14/1362.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i14.1362