Novel virulence factor dupA of Helicobacter pylori as an important risk determinant for disease manifestation: An overview

Figure 1 Schematic representation of the jhp0917, jhp0918 and jhp0919 gene in strain J99 and that of the dupA alleles in the clinical isolates. The long type dupA (2499 nt) in some clinical isolates contained an additional 615 nt in 5' region before jhp0917 gene and ended 5 bp after the start codon of jph0919 gene. The short type dupA (1884 nt) in some clinical isolates starts from the 5' region of jhp0917 gene and ended 5 bp after the start codon of jph0919 gene.

Figure 2 Organization of three types of type IV secretion system in the Helicobacter pylori compared to Agrobacterium tumefaciens prototype type IV secretion system. Genes are not drawn to scale. H. pylori: Helicobacter pylori; A. tumefaciens: Agrobacterium tumefaciens; T4SS: Type IV secretion system.