Mesenterico-portal vein invasion should be an important factor in TNM staging for pancreatic ductal adenocarcinoma: Proposed modification of the 8th edition of the American Joint Committee on Cancer staging system

Figure 1 Type of positive margins in the mesenterico-portal vein- and mesenterico-portal vein+ groups in the West China Hospital database. A: Positive margins in the MPV- group; B: Positive margins in the MPV+ group. MPV: Mesenterico-portal vein.

Figure 2 Survival functions of different American Joint Committee on Cancer stages in the mesenterico-portal vein- and mesenterico-portal vein+ groups. A: Surveillance, epidemiology, and end results database; B: West China Hospital database. AJCC: American Joint Committee on Cancer; MPV: Mesenterico-portal vein; SEER: Surveillance, epidemiology, and end results.

Figure 3 Further comparisons of the survival functions. A: Between patients with different T stages with or without mesenterico-portal vein invasion; B: Between patients with stage IIA and subgroups of stage IIB; C: Between patients with T1N0, T2N0, and T1N1; D: Between patients with T3N1 and T1-3N2. MPV: Mesenterico-portal vein.

Figure 4 Comparison of the 8^th edition of the American Joint Committee on Cancer staging system and the modified staging system in predicting prognosis. A: Surveillance, Epidemiology, and End Results (SEER) database grouping with the 8th edition American Joint Committee on Cancer (AJCC) stage; B: SEER database grouping with the modified stage; C: West China Hospital database grouping with the 8th edition AJCC stage; D: West China Hospital database grouping with the modified stage. AJCC: American Joint Committee on Cancer; SEER: Surveillance, Epidemiology, and End Results.