Preliminary application of 3D-printed coplanar template for iodine-125 seed implantation therapy in patients with advanced pancreatic cancer

Figure 1 3D-printed coplanar template appearance. A: A 3D-printed coplanar template was located on the patient’s skin at the entry point. The implantation needles were inserted into the lesions through the puncture holes. B: The computed tomography manifestation of the 3D-printed coplanar template (arrowhead). C: The position of the implantation needles (arrowhead) and iodine-125 seeds (arrow)

Figure 2 The procedure for 3D-printed coplanar template-assisted iodine-125 seed implantation and dosimeter analysis. A: Preoperative computed tomography demonstrated a pancreatic uncinate process carcinoma. B: A preoperative treatment planning system was used to program the puncture route and iodine-125 seed distribution. The pseudo green color indicated the designed V90 area, and the red points were the ideal iodine-125 seed position. C: With 3D-printed coplanar template assistance, the implantation needles were inserted in a parallel fashion into the lesion to avoid vessels and traversing the intestine. D: Postoperative dosimeter analysis demonstrated the V90 area (green color region) covering the entire tumor.

Figure 3 Hemorrhage post-procedure and iodine-125 seed migration in the lesion. A: Peritoneal hematoma (arrow) due to mesenteric vein injury. B: Iodine-125 seed migration in the pancreatic head lesion.