Risk of lymph node metastases in patients with T1b oesophageal adenocarcinoma: A retrospective single centre experience

Figure 1 Superficially invasive T1b oesophageal adenocarcinoma. A: Low power overview of the lesion. A moderately differentiated oesophageal adenocarcinoma is located at the squamocolumnar junction. This is a piecemeal excision of this lesion. The deep margin is clear (R0). There was no lymphovascular invasion or poor differentiation. Boxed area shown in B. B: High power of the invasive front showing a tumour gland just penetrating the original muscularis mucosae (asterisk).

Figure 2 Flowchart depicting patient subgroups and outcomes. Overall median follow-up 41 mo (IQR 26-53). OAC: Oesophageal adenocarcinoma; LR: Low-risk tumour; HR: High-risk tumour; IQR: Interquartile range.

Figure 3 Kaplan-Meier disease-specific survival curve of all patients treated conservatively and surgically. There was no statistically significant difference (excluded were 10 patients from conservative group who died of non-oesophageal adenocarcinoma-related cause).

Figure 4 Kaplan-Meier disease-specific survival curve of patients with high-risk tumours treated conservatively and surgically (excluded were 7 patients from high-risk-conservative group who died of non-oesophageal adenocarcinoma-related cause). There was no statistically significant difference, although a trend towards a better survival of surgery patients is observed.