Copyright ©The Author(s) 2018.
World J Gastroenterol. Aug 14, 2018; 24(30): 3347-3360
Published online Aug 14, 2018. doi: 10.3748/wjg.v24.i30.3347
Figure 1
Figure 1 Associations within the human leukocyte antigen locus identified by genome-wide association studies for hepatitis B virus-related traits. GWAS hits for HBV-related pathologies are concentrated on the HLA region. Top SNPs in each GWAS are demonstrated in rows in the chronological order of publication; red for HBV persistence, green for Hepatitis B vaccine non-response, and blue for advanced HBV-related liver diseases. The nearest genes for the identified SNPs are colored in red; HLA-A and HLA-B are also marked. GWAS: Genome-wide association studies; HLA: Human leukocyte antigen; HBV: Hepatitis B virus; SNPs: Single nucleotide polymorphisms.