Prognostic significance of pretreatment serum carcinoembryonic antigen levels in gastric cancer with pathological lymph node-negative: A large sample single-center retrospective study

Figure 1 Inclusion and exclusion criteria. CEA: Carcinoembryonic antigen.

Figure 2 Division of patients by the cut-off points produced by X-tile plot. X-tile plots for CEA. The produced log-rank χ² value stratifies the pTxN0M0 GC patients into two groups by a cut-off value 30.02 ng/mL, showing a strong discriminatory capacity, with a χ² value of 85.15 and a relative risk ratio of 1:2.15. CEA: Carcinoembryonic antigen.

Figure 3 Survival analysis of pN0 patients with gastric cancer undergoing curative intent surgery. The P values for the survival comparison was determined by the log-rank test. CEA: Carcinoembryonic antigen.

Figure 4 Univariate and multivariate analyses for pN0 gastric cancer patients using the Cox regression model. A: HR was calculated in multivariate analyses; B: HR was calculated in CEA-low group; C: HR was calculated for CEA-high group. CEA: Carcinoembryonic antigen; HR: Hazard ratio.