Novel predictors for lymph node metastasis in submucosal invasive colorectal carcinoma

Figure 1 Representative histopathological micrograph of tumor budding (magnification × 400). Hematoxylin and eosin staining of a tumor section showing tumor budding (black arrows) at the invasive front.

Figure 2 Representative histopathological micrograph of poorly differentiated clusters (magnification × 400). Hematoxylin and eosin stain of tumor section showing cancer cell clusters of ≥ 5 carcinoma cells lacking a glandular formation (poorly differentiated clusters, black arrows).

Figure 3 Comparison of receiver operating characteristic curves by multivariate logistic regression tests. Desmoplaisa and tumor type were used as compounding factors.